Research Article

Hospital-acquired infections and antibiotic use in a geriatric hospital: a point prevalence study

Vittorio Marconi, Corinna Fortunato*, Davide Mengarelli detto Rinaldini, Lidia Pascucci, Daniele Arsego and Letizia Ferrara

Published: 03 March, 2023 | Volume 7 - Issue 1 | Pages: 004-007

Background: Healthcare-Associated Infections (HAIs) are the most common healthcare-associated complications, particularly in elderly patients. The aim of this study is to describe the prevalence of HAIs and associated risk factors in the IRCCS INRCA of Ancona.
Methods: A cross-sectional study has been carried out. Data has been collected in accordance with the European Centre for Disease Prevention and Control (ECDC) Point Prevalence Survey 2022-2023 (PPS3) protocol in the IRCCS INRCA of Ancona in November 2022.
Results: Out of the 128 patients included in our study, 75.0% were over 78 years old and 9.1% presented an active HAI on the day of the survey. The prevalence of HAIs varied based on the length of the hospital stay (OR 1.1, CI 95% 1.05 - 1.17, p < 0.001) and hospitalization > 7 days (OR 5.9, CI 95% 1.2 - 28.7, p = 0.02).
Conclusion: It is clear from our findings that HAIs are associated with advanced patient age, prolonged hospital stay, and use of medical devices, especially in those patients that, due to their clinical situation, are more vulnerable. Although some of these infections can easily be treated, it is important to develop effective infection control strategies thanks to antimicrobial stewardship programs.

Read Full Article HTML DOI: 10.29328/journal.apps.1001037 Cite this Article Read Full Article PDF


  1. Haque M, Sartelli M, McKimm J, Abu Bakar M. Health care-associated infections - an overview. Infect Drug Resist. 2018 Nov 15;11:2321-2333. doi: 10.2147/IDR.S177247. PMID: 30532565; PMCID: PMC6245375.
  2. Suetens C, Latour K, Kärki T, Ricchizzi E, Kinross P, Moro ML, Jans B, Hopkins S, Hansen S, Lyytikäinen O, Reilly J, Deptula A, Zingg W, Plachouras D, Monnet DL; Healthcare-Associated Infections Prevalence Study Group. Prevalence of healthcare-associated infections, estimated incidence and composite antimicrobial resistance index in acute care hospitals and long-term care facilities: results from two European point prevalence surveys, 2016 to 2017. Euro Surveill. 2018 Nov;23(46):1800516. doi: 10.2807/1560-7917.ES.2018.23.46.1800516. Erratum in: Euro Surveill. 2018 Nov;23(47): PMID: 30458912; PMCID: PMC6247459.
  3. Versporten A, Zarb P, Caniaux I, Gros MF, Drapier N, Miller M, Jarlier V, Nathwani D, Goossens H; Global-PPS network. Antimicrobial consumption and resistance in adult hospital inpatients in 53 countries: results of an internet-based global point prevalence survey. Lancet Glob Health. 2018 Jun;6(6):e619-e629. doi: 10.1016/S2214-109X(18)30186-4. Epub 2018 Apr 23. Erratum in: Lancet Glob Health. 2018 Sep;6(9):e968. PMID: 29681513.
  4. Christaki E, Marcou M, Tofarides A. Antimicrobial Resistance in Bacteria: Mechanisms, Evolution, and Persistence. J Mol Evol. 2020 Jan;88(1):26-40. doi: 10.1007/s00239-019-09914-3. Epub 2019 Oct 28. PMID: 31659373.
  5. Vandael E, Latour K, Goossens H, Magerman K, Drapier N, Catry B, Versporten A; Belgian Point Prevalence Survey Study Group. Point prevalence survey of antimicrobial use and healthcare-associated infections in Belgian acute care hospitals: results of the Global-PPS and ECDC-PPS 2017. Antimicrob Resist Infect Control. 2020 Jan 13;9(1):13. doi: 10.1186/s13756-019-0663-7. PMID: 31956402; PMCID: PMC6958935.
  6. World Health Organization. Global action plan on antimicrobial resistance. World Health Organization. ‎2015‎. https://apps.who.int/iris/handle/10665/193736
  7. ISTAT (2022) - Previsioni della popolazione residente e delle famiglie - https://www.istat.it/it/files//2022/09/REPORT-PREVISIONI-DEMOGRAFICHE-2021.pdf
  8. Giarratano A, Green SE, Nicolau DP. Review of antimicrobial use and considerations in the elderly population. Clin Interv Aging. 2018 Apr 17;13:657-667. doi: 10.2147/CIA.S133640. PMID: 29713150; PMCID: PMC5909780.
  9. Point prevalence survey of healthcare-associated infections and antimicrobial use in European acute care hospitals. Protocol version 6.1, ECDC PPS 2022-2023. https://www.ecdc.europa.eu/sites/default/files/documents/antimicrobial-use-healthcare-associated-infections-point-prevalence-survey-version6-1.pdf
  10. Russo Fiorino G, Maniglia M, Marchese V, Aprea L, Torregrossa MV, Campisi F, Favaro D, Calamusa G, Amodio E. Healthcare-associated infections over an eight year period in a large university hospital in Sicily (Italy, 2011-2018). J Infect Prev. 2021 Sep;22(5):220-230. doi: 10.1177/17571774211012448. Epub 2021 Jun 22. PMID: 34659460; PMCID: PMC8512876.
  11. Wolkewitz M, Schumacher M, Rücker G, Harbarth S, Beyersmann J. Estimands to quantify prolonged hospital stay associated with nosocomial infections. BMC Med Res Methodol. 2019 May 31;19(1):111. doi: 10.1186/s12874-019-0752-6. PMID: 31151418; PMCID: PMC6544970.
  12. Ssekitoleko RT, Oshabaheebwa S, Munabi IG, Tusabe MS, Namayega C, Ngabirano BA, Matovu B, Mugaga J, Reichert WM, Joloba ML. The role of medical equipment in the spread of nosocomial infections: a cross-sectional study in four tertiary public health facilities in Uganda. BMC Public Health. 2020 Oct 16;20(1):1561. doi: 10.1186/s12889-020-09662-w. PMID: 33066745; PMCID: PMC7562759.
  13. Sharif M, Aslam S, Saleem Z. Point prevalence survey to estimate antimicrobial use in a tertiary care university hospital in Pakistan using WHO methodology: findings and implications. Infect Dis (Lond). 2022 Sep;54(9):698-701. doi: 10.1080/23744235.2022.2064544. Epub 2022 Apr 19. PMID: 35439103.
  14. Maurici M, D'Alò GL, Fontana C, Santoro V, Gaziano R, Ciotti M, Cicciarella Modica D, De Filippis P, Sarmati L, De Carolis G, Pica F. Microbiology and Clinical Outcome of Hospital-Acquired Respiratory Infections in an Italian Teaching Hospital: A Retrospective Study. Healthcare (Basel). 2022 Nov 12;10(11):2271. doi: 10.3390/healthcare10112271. PMID: 36421594; PMCID: PMC9691183.


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