Figure 1

Significance and Prospect of Brf1 Overexpression

Liling Zheng*, Yongluan Lin, Zaifa Hong, Dongyan Shen and Shuping Zhong*

Published: 22 August, 2023 | Volume 7 - Issue 1 | Pages:

apps-aid1043-g001

Figure 1:

Figure 1: Brf1 overexpression promotes development of breast cancer. Alcohol augments ERα activity through JNK1 pathway. ERα increases the cellular levels of Runx2, resulting in upregulation of Brf1 and RNA Pol III genes, eventually promotes breast cancer development. While Tam reduces Brf1 expression in ER+ breast cancer cells. ↓: enhancement; ┴: repression.

Read Full Article HTML DOI: 10.29328/journal.apps.1001043 Cite this Article Read Full Article PDF

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