Figure 2

Significance and Prospect of Brf1 Overexpression

Liling Zheng*, Yongluan Lin, Zaifa Hong, Dongyan Shen and Shuping Zhong*

Published: 22 August, 2023 | Volume 7 - Issue 1 | Pages:

apps-aid1043-g002

Figure 2:

Figure 2: Alcohol and DEN increase Brf1 expression. Alcohol activates JNK1 to enhance c-Jun activity. Alcohol also activates MSK1 pathway. Both pathways enhance Brf1 expression and RNA Pol III gene transcription. While DEN induces histone H3 phosphorylation to increase Brf1 expression by epigenetically modulating, Finally, they facilities HCC occurrences, ↓: enhancement; ┴: repression.

Read Full Article HTML DOI: 10.29328/journal.apps.1001043 Cite this Article Read Full Article PDF

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