Revisiting carotenoid aggregates discerning non-covalent interaction of unbranched fatty acid analogues

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Submitted: March 21, 2022
Published: Mar 31, 2022
DOI: 10.29328/journal.apps.1001028
Keywords:
Exciton coupling, Dihedral angle, Types of aggregates, Overlay angle, Lipid additives

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Miklós Simonyi
Research Center for Natural Sciences, Institute of Organic Chemistry, Budapest, Hungary

Abstract

Certain carotenoid aggregates provide scaffolds of moderate stability characterized by their CD spectra. The interaction of the scaffold with small lipid molecules either destabilize, or reinforce its structure. The idea can be applied to open-chain fatty acids and some analogues. Fatty acids and fatty alcohol decrease exciton intensity of the aggregate, while esters of both alcohol and acids increase it. Moreover, the stabilizing effect depends on chain-length. Thus, the scaffold distinguishes compounds that either loosen its structure, or reinforce it.

Article Details

Simonyi, M. (2022). Revisiting carotenoid aggregates discerning non-covalent interaction of unbranched fatty acid analogues. Archives of Pharmacy and Pharmaceutical Sciences, 6(1), 001–005. https://doi.org/10.29328/journal.apps.1001028
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Copyright (c) 2022 Simonyi M.

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